base_editing_design

shallow

com.seqbench/workbench · Verify this server

Design cytosine (CBE, C→T) or adenine (ABE, A→G) base-editing gRNAs for an SpCas9 target: for each NGG gRNA it reports every editable base inside the editor's activity window, flags bystander edits (more than one editable base in the window), and — with a CDS reading frame — classifies each edit's amino-acid consequence (silent / missense / nonsense / stop-loss). Bystander-free guides are ranked first. Handles both strands (a C→T on the protospacer of a reverse-strand guide is reported as the forward-strand G→A).

100.0/100

1 trials · measured 55 days ago

base_editing_design scores 100.0/100 on Vouch's measured behaviour index, from 1 real invocation trials against com.seqbench/workbench, measured 25 Aug 2026 under methodology v0.2.0. Every measured component scored 100.

Component breakdown

ComponentWeightValue
Reliability35%not applicable
Schema integrity25%100.0
Failure behaviour15%not applicable
Latency15%not applicable
Concurrency10%not applicable

Tool details

Transport
remote
Credential class
unreachable
Input schema
not declared
Output schema
not declared
Side-effect classification
unclassified

Score history

DayScoreTierMethodology
2026-08-25100.0shallowv0.2.0

Probe evidence

ProbeOutcomes
schema_integritypass: 1

Raw request/response logs are not archived yet — the outcome counts above are drawn directly from every recorded trial.

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Vouch score: base_editing_design
[![Vouch score](https://vouch.tools/api/tools/ec782ae8-5b01-4ecf-8229-09c739e0be9a/badge.svg)](https://vouch.tools/tools/ec782ae8-5b01-4ecf-8229-09c739e0be9a)
base_editing_design — Vouch