string_ppi_enrichment

org.string-db/string-mcp · Verify this server

This tool tests if your network is enriched in protein-protein interactions compared to the background proteome-wide distribution (i.e., if your proteins are more functionally connected than expected by chance). - The enrichment is assessed using the actual observed edges versus expected edges in a random network of the same size. - The p-value reflects the likelihood that your observed number of interactions would occur by chance. - Report the p-value as a human-readable value (e.g. 2.3e-5 or 0.023). When calling related tools use the same input parameters unless otherwise specified. Output fields: - number_of_nodes: Number of proteins in your network - number_of_edges: Number of observed edges/interactions - average_node_degree: Mean degree (average number of interactions per node) - local_clustering_coefficient: Average clustering coefficient in the network - expected_number_of_edges: Expected number of edges in a random network of the same size - p_value: p-value for network enrichment (smaller = more enriched) Example identifiers: "SMO%0dTP53"