crispr_grna_design
shallowcom.seqbench/workbench · Verify this server
Find and score candidate guide RNAs (protospacer + PAM) in a target DNA for common nucleases (SpCas9, SpCas9-NG, SaCas9, Cas12a). PREDICTED, NOT MEASURED. No held-out skill statistic is claimed. Both are pre-2016 models superseded in accuracy by Rule Set 2 / Azimuth and by DeepSpCas9, neither of which is shipped here. Treat the ordering as a ranking aid, not an efficiency prediction. Valid for: SpCas9 with an NGG PAM and a 20 nt spacer, and only when enough genomic flanking context is present to build the model's 30-mer / 35-mer window — both scores are null rather than padded otherwise. Nothing is predicted for SaCas9, Cas12a or SpCas9-NG.
1 trials · measured 8 days ago
crispr_grna_design scores 100.0/100 on Vouch's measured behaviour index, from 1 real invocation trials against com.seqbench/workbench, measured 25 Aug 2026 under methodology v0.2.0. Every measured component scored 100.
Component breakdown
| Component | Weight | Value |
|---|---|---|
| Reliability | 35% | not applicable |
| Schema integrity | 25% | 100.0 |
| Failure behaviour | 15% | not applicable |
| Latency | 15% | not applicable |
| Concurrency | 10% | not applicable |
Tool details
- Transport
- remote
- Credential class
- self-provisionable
- Input schema
- not declared
- Output schema
- not declared
- Side-effect classification
- unclassified
Score history
| Day | Score | Tier | Methodology |
|---|---|---|---|
| 2026-08-25 | 100.0 | shallow | v0.2.0 |
Probe evidence
| Probe | Outcomes |
|---|---|
| schema_integrity | pass: 1 |
Raw request/response logs are not archived yet — the outcome counts above are drawn directly from every recorded trial.
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