io.github.SidneyBissoli/medical-terminologies-mcp

Tools

• atc_classify

  Look up the WHO ATC (Anatomical Therapeutic Chemical) classification(s) for a drug by name. Use this tool to: - Find the ATC code for a medication (e.g., "metformin" → A10BA02) - Identify the therapeutic and pharmacological class hierarchy - Cross-reference drugs with their international ATC codes Returns one entry per ATC code the drug belongs to. A single-ingredient drug typically maps to one substance-level code; combination products map to multiple. ATC codes are international (WHO Collaborating Centre); this tool retrieves them via NLM RxClass.

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• atc_lookup

  Look up an ATC code at level 1-4 to get its name and hierarchy level. Use this tool to: - Resolve an ATC code (e.g., "A10BA") to its class name ("Biguanides") - Confirm a code exists in the current ATC index - Identify the level (anatomical / therapeutic / pharmacological / chemical) Accepts codes 1-5 characters long: "A" (anatomical), "A10" (therapeutic), "A10B" (pharmacological), "A10BA" (chemical). Substance-level codes (7 chars, e.g., "A10BA02") are not exposed by this endpoint — use atc_classify with the drug name to retrieve the substance code.

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• atc_members

  List the drugs (substances) that belong to an ATC class. Use this tool to: - Enumerate all members of a therapeutic class (e.g., "A10BA" → metformin, phenformin) - Build a list of drugs sharing a pharmacological mechanism - Explore an ATC subtree at any level Each member includes its substance-level (7-char) ATC code via source_atc_code, useful for disambiguation when the queried class is at level 1-4. RxNorm's catalog is US-centric; the ATC class names and codes themselves are international.

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• cid10_chapter

  Get one CID-10 chapter and its constituent groups (e.g., "Chapter IX → I00-I02 Febre reumática aguda, I05-I09 Doenças reumáticas crônicas do coração, ..."). Use this tool to: - Drill from a chapter into its groups - Build hierarchical browsers - Find which group contains a code range Provide a chapter number (1-22).

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• cid10_chapters

  List the 22 chapters of CID-10 with their code ranges and Portuguese titles. Use this tool to: - See the top-level structure of CID-10 (chapters I-XXII, e.g., "I. Algumas doenças infecciosas e parasitárias", "IX. Doenças do aparelho circulatório") - Map a code to its chapter by code range (e.g., I00-I99 → chapter IX) - Build a navigable table of contents for downstream tooling Returns 22 entries — CID-10 V2008 has not been updated since 2008.

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• cid10_lookup

  Look up a specific CID-10 code and return its Portuguese name. Use this tool to: - Resolve a code to its Brazilian description ("I21" → "Infarto agudo do miocárdio") - Confirm a 3-char category or 4-char subcategory exists in CID-10 - Retrieve gender / cause-of-death restriction flags when applicable Accepts both dotted ("A00.1") and undotted ("A001") forms; returns the canonical display.

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• cid10_search

  Search the Brazilian CID-10 (Classificação Estatística Internacional de Doenças, 10ª Revisão) by Portuguese text. Use this tool to: - Find CID-10 codes for Brazilian SUS / ANVISA contexts ("infarto", "diabetes", "tuberculose") - Look up the official Portuguese (CBCD/USP) translation of a clinical term - Locate codes for billing, epidemiology, and clinical documentation in Brazil Returns matches from CID-10 categories (3-char) and/or subcategories (4-char). Search is diacritic-insensitive: typing "infeccoes" matches "infecções". This tool searches the Brazilian Portuguese CID-10 V2008 — for the international ICD-11 (current WHO revision, in English by default), use icd11_search.

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• find_equivalent

  Ranked unified search for equivalent terms across multiple medical terminologies. Use this tool to: - Find the same concept in different coding systems - Compare how terminologies represent a concept - Support terminology mapping and data integration Searches across: ICD-11, SNOMED CT, LOINC, RxNorm, and MeSH. Set `target_terminologies` to limit which are searched, or set `source_terminology` to exclude one (e.g. when you already have a code from that terminology and want equivalents elsewhere). The two combine: source is subtracted from targets. `limit` caps candidates per terminology (default 5, max 10). Every candidate carries `match_score` (lexical similarity to the search term, 0-1) and `rank` (global position across all searched terminologies) — both computed by this server, since upstreams don't expose comparable relevance scores. Candidates from different terminologies whose titles are lexically identical are clustered in `groups` — a strong same-concept signal (absence of a group is NOT evidence of non-equivalence). Searches upstreams in English. For official pt-BR content, use the dedicated tools: `icd11_search`/`mesh_search` accept `language: "pt"`, and `cid10_search` is natively Portuguese.

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• icd11_chapters

  List all ICD-11 chapters (top-level categories). Use this tool to: - Get an overview of ICD-11 structure - Find which chapter covers a body system or condition type - Navigate to specific disease categories ICD-11 has 28 chapters covering all areas of medicine.

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• icd11_hierarchy

  Navigate the ICD-11 hierarchy to find parent or child entities. Use this tool to: - Find broader categories (parents) of a condition - Find specific subtypes (children) of a condition - Understand the classification structure Direction 'parents' returns ancestor categories, 'children' returns subcategories.

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• icd11_lookup

  Get detailed information about a specific ICD-11 entity by code or URI. Use this tool to: - Get the full definition of a disease - Retrieve coding notes and exclusions - Get the official title and synonyms Provide either an ICD-11 code (e.g., "BA00") or a full foundation URI. Set `language` for WHO's official translations (e.g. `language: "pt"` for official Portuguese).

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• icd11_postcoordination

  Get postcoordination information for an ICD-11 code. Use this tool to: - Find available axes for building composite codes - Check required vs optional postcoordination - Understand code extension possibilities Postcoordination allows adding severity, laterality, anatomy, etc.

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• icd11_search

  Search for medical conditions, diseases, and health problems in ICD-11 (International Classification of Diseases, 11th Revision). Use this tool to: - Find ICD-11 codes for diagnoses - Search for diseases by name or keyword - Look up conditions in multiple languages Set `language` for WHO's official translations — e.g. `language: "pt"` searches and returns the official Portuguese (pt-BR) ICD-11 labels. Never machine-translated. Returns matching entities with codes, titles, and relevance scores.

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• loinc_answers

  Get the list of valid answers for a LOINC questionnaire item. Use this tool to: - Find valid response options for survey questions - Get answer codes for data entry validation - Look up standardized answer lists Only applicable to LOINC codes that represent questions with defined answer sets.

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• loinc_details

  Get detailed information about a specific LOINC code. Use this tool to: - Get the full name and description of a LOINC code - Find the component, property, timing, and system - Check the scale type and method Provide a LOINC number in format "XXXXX-X" (e.g., "2339-0" for Glucose).

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• loinc_panels

  Get the structure of a LOINC panel or form. Use this tool to: - See all tests included in a panel (e.g., CBC, metabolic panel) - Get the structure of assessment forms - Find related observations grouped together Returns the list of LOINC codes that make up the panel.

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• loinc_search

  Search for laboratory tests, clinical observations, and measurements in LOINC (Logical Observation Identifiers Names and Codes). Use this tool to: - Find LOINC codes for lab tests (e.g., "glucose", "hemoglobin") - Search for clinical measurements and vital signs - Look up diagnostic observations Returns matching LOINC codes with names, components, and properties.

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• map_icd10_to_icd11

  Authoritative ICD-10 → ICD-11 mapping using WHO transition tables (release 2025-01, bundled with the server). Returns the primary 1:1 ICD-11 category for the ICD-10 code plus any alternative ICD-11 candidates that WHO documents (some ICD-10 concepts split into multiple ICD-11 entities). For each mapping, includes the ICD-11 code, title, chapter, and the Foundation URI / Linearization URI for navigating to the full entity definition. Use this for clinical coding, billing migration, retrospective analysis, and any workflow that needs authoritative mapping rather than text-search candidates. Coverage: 11,243 ICD-10 categories (excludes chapters and blocks like "A00-A09" which aren't used in clinical coding). Provide a code like "E11" (Type 2 diabetes), "I21" (Acute MI), or "A07.8" (4 alternatives in WHO's table). Both dotted ("A07.8") and undotted ("A078") forms are accepted. Returns "no mapping" when the code isn't in the WHO category-level table — that's the honest answer rather than a fuzzy search fallback.

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• map_loinc_to_snomed

  This tool looks up a LOINC code in NLM Clinical Tables and returns guidance on where to obtain a LOINC → SNOMED CT mapping. It does not perform the mapping. Direct LOINC → SNOMED CT mappings are not freely available via API. UMLS Metathesaurus contains the relationships but requires an individual UMLS Terminology Services license; the LOINC SNOMED CT Expression Association is published by Regenstrief Institute as part of the LOINC release and requires authenticated download from loinc.org under the LOINC license. For programmatic LOINC → SNOMED mapping, use UMLS or the LOINC Expression Association files. For interactive lookup, use the SNOMED CT browser available to your organization or the Regenstrief RELMA desktop tool. Provide a LOINC code like "2339-0" (Glucose) or "718-7" (Hemoglobin).

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• mesh_descriptor

  Get detailed information about a MeSH descriptor by ID. Use this tool to: - Get the full definition (scope note) of a MeSH term - View tree numbers showing hierarchy location - See related concepts and synonyms Provide a MeSH Descriptor ID like "D015242" (Ofloxacin). Set `language` to request NLM's official translations where they exist (e.g. `language: "pt"`).

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• mesh_qualifiers

  Get allowed qualifiers (subheadings) for a MeSH descriptor. Use this tool to: - Find which qualifiers can be combined with a descriptor - Build precise MeSH search queries - Understand aspects that can be specified Qualifiers refine descriptors (e.g., "Diabetes Mellitus/drug therapy").

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• mesh_search

  Search for MeSH (Medical Subject Headings) descriptors. Use this tool to: - Find MeSH terms for indexing medical literature - Look up subject headings for PubMed searches - Find controlled vocabulary terms Set `language` to request NLM's official translations where they exist (e.g. `language: "pt"` for Portuguese labels); content is never machine-translated. Returns matching descriptors with MeSH IDs and labels.

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• mesh_tree

  Get the tree hierarchy location(s) for a MeSH descriptor. Use this tool to: - See where a term fits in the MeSH hierarchy - Understand broader/narrower relationships - Find related terms in the same branch MeSH tree numbers show the hierarchical path (e.g., C14.280.647 for Myocardial Infarction).

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• rxnorm_classes

  Get therapeutic and pharmacologic classes for a drug. Use this tool to: - Find the drug class (e.g., "Beta-blockers", "NSAIDs") - Identify therapeutic categories - Look up mechanism of action classifications Returns class IDs, names, and classification sources.

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• rxnorm_concept

  Get detailed information about a specific RxNorm concept by RxCUI. Use this tool to: - Get the full name and synonyms for a drug - Check the concept status (active, remapped, etc.) - View related concepts (ingredients, brands, forms) Provide an RxCUI (RxNorm Concept Unique Identifier) like "161".

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• rxnorm_ingredients

  Get active ingredients for a drug by RxCUI. Use this tool to: - Find the active ingredients in a medication - Check for single vs. multiple ingredient products - Identify the generic components of brand drugs Returns ingredient RxCUIs and names.

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• rxnorm_ndc

  Map between RxNorm concepts and National Drug Codes (NDC). Use this tool to: - Get all NDC codes for a drug (by RxCUI) - Find the RxCUI for an NDC code - Cross-reference between coding systems Provide either an RxCUI to get NDCs, or an NDC to get the RxCUI.

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• rxnorm_search

  Search for drugs in RxNorm (Normalized names for clinical drugs). Use this tool to: - Find drug concepts by brand or generic name - Look up medications for prescribing - Search for drug formulations Returns matching drugs with RxCUI identifiers, names, and term types.

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• terminology_diff

  Report what diff data is available between two versions of a terminology. For most terminologies this is **guidance only** — the server doesn't ship historical snapshots, so the tool points at the publisher's official changelog and explains the cadence. `bundled_versions` lists the version(s) this server actually has on hand. For **ICD-10 vs ICD-11** specifically, the tool surfaces a real cross-revision summary from the bundled WHO transition tables (the ICD-10 → ICD-11 case is a structural diff between two WHO revisions). Use `terminology: "icd10"` with no `to_version` to get the cross-revision summary: total mapped ICD-10 categories, how many are 1:1 vs split into multiple ICD-11 codes, and the average number of alternatives when split. Inputs: - `terminology` (required): which terminology to report on. - `from_version` (optional): the version you have data from. If omitted, the tool reports against the currently-bundled version. - `to_version` (optional): the version you want to compare to. If omitted, the tool reports against the publisher's latest known release. This tool is intentionally a metadata + guidance layer, not a diff engine — for terminologies that change frequently (SNOMED, LOINC, RxNorm, MeSH), the publisher's official changelog is the authoritative source.

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• terminology_versions

  List the current version, release date, publisher, source URL, and update cadence of every terminology this server queries against. Useful for pipeline maintainers who need to: - Confirm which release of ICD-11 / SNOMED / LOINC / RxNorm / MeSH / ATC the server is querying before a batch run. - Verify the bundled CID-10 (frozen at V2008) and ICD-10 → ICD-11 transition tables (currently 2025-01) match expectations. - Cite the data version in research artifacts. Pass `terminology` to filter to a single entry; otherwise the full set of 8 is returned. The ICD-10 → ICD-11 version reads live from the bundled dataset; everything else is metadata maintained alongside the project release.

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• validate_codes

  Validate a mixed batch of medical codes against their source terminologies. Useful for retrospective analysis of legacy databases — flag codes that no longer exist, surface ICD-10 → ICD-11 replacements, and grade activity status where the terminology exposes it. For each input `{ code, terminology }`, returns: - **valid**: whether the code exists in the source terminology. - **active**: whether the code is currently active. Null when the source doesn't expose an explicit active/inactive distinction at category level (CID-10, ATC, ICD-11, RxNorm, MeSH all return null today; SNOMED and LOINC return a real boolean). - **title**: the official label/name when available. - **replaced_by**: a successor code, populated today only for ICD-10 codes that have a primary ICD-11 mapping in the bundled WHO transition tables. - **source**: human-readable provenance of the validation (terminology + release/version). - **error**: non-null only when validation couldn't be performed (network error, SNOMED feature flag off, etc.). `valid: false` + `error: null` means "code not found"; `valid: false` + `error: set` means "couldn't validate". Terminology is **required per code** — auto-detection isn't supported because category codes like "A00" exist in both ICD-10 and CID-10. Accepted values: `icd11`, `icd10`, `snomed`, `loinc`, `rxnorm`, `mesh`, `atc`, `cid10`. Hard cap of 50 codes per call; codes are validated in parallel through their respective clients, so total wall time scales with the slowest upstream + its rate limit (worst case ~10 s for a full batch hitting ICD-11).

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